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The proposed relationship between cytosolic copper, gene expression and differentiation is summarised in Fig.

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Other genes down-regulated in the Wt80Cu cultures were: SCO , a putative glycosyl hydrolase supposedly repressed by CsoR 15 ; and SCO , a cyclic AMP receptor protein homologue whose mutation was reported to diminish germination

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However, the biomolecular mechanisms controlling germination remain poorly characterised 6 , 7.

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Secondary Metabolites Produced during the Germination of Streptomyces coelicolor.

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Description: Metal sensitive transcriptional repressors can bind zinc, and also copper, which has been demonstrated, for instance, in the case of CsoR from Bacillus subtilis

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